{"id":9542,"date":"2026-02-04T04:27:57","date_gmt":"2026-02-04T04:27:57","guid":{"rendered":"https:\/\/changhongchemical.com\/?p=9542"},"modified":"2026-04-27T11:16:13","modified_gmt":"2026-04-27T11:16:13","slug":"from-i2959-to-lap-my-journey-of-upgrading-hydrogel-photocuring-technology","status":"publish","type":"post","link":"https:\/\/changhongchemical.com\/zh\/from-i2959-to-lap-my-journey-of-upgrading-hydrogel-photocuring-technology\/","title":{"rendered":"\u4ece I2959 \u5230 LAP\uff1a\u6211\u7684\u6c34\u51dd\u80f6\u5149\u56fa\u5316\u6280\u672f\u5347\u7ea7\u4e4b\u65c5"},"content":{"rendered":"<h1><strong>\u4ece I2959 \u5230 LAP\uff1a\u6211\u7684\u6c34\u51dd\u80f6\u5149\u56fa\u5316\u6280\u672f\u5347\u7ea7\u4e4b\u65c5<\/strong><\/h1>\r\n\u5927\u5bb6\u597d\uff0c\u6211\u662f Starry\u3002\u6211\u5728\u5b9e\u9a8c\u5ba4\u7814\u7a76\u5149\u56fa\u5316\u6750\u6599\u5df2\u6709\u5341\u591a\u5e74\u3002\u5982\u679c\u60a8\u6b63\u4e3a\u6c34\u51dd\u80f6\u56fa\u5316\u4e0d\u5747\u5300\u6216\u751f\u7269\u6253\u5370\u4e2d\u7ec6\u80de\u5b58\u6d3b\u7387\u4e0d\u7406\u60f3\u800c\u82e6\u607c\uff0c\u6216\u8005\u60a8\u6b63\u4e3a\u4f20\u7edf\u5149\u5f15\u53d1\u5242 I2959 \u7684\u5e38\u89c1\u95ee\u9898\u800c\u6cae\u4e27\uff0c\u90a3\u4e48\u60a8\u6765\u5bf9\u5730\u65b9\u4e86\u3002\u4eca\u5929\uff0c\u6211\u5c06\u4e0e\u60a8\u5206\u4eab\u6211\u7684\u6210\u529f\u4e0e\u5931\u8d25\u7ecf\u9a8c\uff0c\u5e76\u8be6\u7ec6\u8ba8\u8bba \"\u660e\u661f \"\u5149\u5f15\u53d1\u5242 LAP\uff0c\u8ba9\u60a8\u4e0d\u4ec5\u80fd\u4e86\u89e3\u5b83\u4e3a\u4f55\u5982\u6b64\u51fa\u8272\uff0c\u8fd8\u80fd\u5b66\u4e60\u5982\u4f55\u6709\u6548\u4f7f\u7528\u5b83\u3002\r\n\r\n<strong><b>I.\u4e3a\u4ec0\u4e48 LAP \u88ab\u8ba4\u4e3a\u662f\u751f\u7269\u533b\u5b66\u6c34\u51dd\u80f6\u7684 \"\u6e38\u620f\u89c4\u5219\u6539\u53d8\u8005\"\uff1f<\/b><\/strong>\r\n\r\n\u8bb0\u5f97\u4e03\u516b\u5e74\u524d\uff0c\u6211\u4eec\u5b9e\u9a8c\u5ba4\u53ea\u4f7f\u7528 I2959\u3002\u8fd9\u662f\u4e00\u6b3e\u53ef\u9760\u7684 \"\u8001\u9ec4\u725b\"\uff0c\u4f46\u968f\u7740\u6211\u4eec\u7684\u7ec6\u80de\u5305\u88ab\u5b9e\u9a8c\u8d8a\u6765\u8d8a\u590d\u6742\uff0c\u95ee\u9898\u4e5f\u968f\u4e4b\u800c\u6765\uff1a\u6eb6\u89e3\u901f\u5ea6\u6162\u3001\u9700\u8981\u7d2b\u5916\u56fa\u5316\u3001\u751f\u7269\u76f8\u5bb9\u6027\u4e0d\u8db3\u3002\u76f4\u5230 LAP \u8fdb\u5165\u6211\u7684\u89c6\u91ce\uff0c\u6574\u4e2a\u5de5\u4f5c\u6d41\u7a0b\u624d\u771f\u6b63\u53d8\u5f97\u987a\u7545\u3002\r\n<h4><strong>LAP \u7684\u6838\u5fc3\u4f18\u52bf\u8fdc\u4e0d\u6b62 \"\u826f\u597d\u7684\u6c34\u6eb6\u6027 \"\u8fd9\u4e48\u7b80\u5355\u3002<\/strong><\/h4>\r\n\u5176\u6700\u5927\u7684\u521b\u65b0\u5728\u4e8e\uff0c\u5728 405 \u7eb3\u7c73\u7684\u7ec6\u80de\u53cb\u597d\u84dd\u5149\u7a97\u53e3\u5185\uff0c\u5c06\u9ad8\u6548\u5149\u5f15\u53d1\u4e0e\u51fa\u8272\u7684\u751f\u7269\u76f8\u5bb9\u6027\u5b8c\u7f8e\u5730\u7ed3\u5408\u5728\u4e00\u8d77\u3002\u8fd9\u5c31\u597d\u6bd4\u4e3a\u7cbe\u7ec6\u7684\u5916\u79d1\u624b\u672f\u914d\u5907\u4e86\u4e00\u628a\u66f4\u950b\u5229\u3001\u66f4\u5b89\u5168\u7684\u624b\u672f\u5200\u3002\u6211\u8fdb\u884c\u4e86\u5bf9\u6bd4\u5b9e\u9a8c\uff1a\u5728\u76f8\u540c\u7684 GelMA \u9884\u805a\u7269\u6eb6\u6db2\u4e2d\uff0c0.1%\uff08w\/v\uff09LAP \u5728 405 \u7eb3\u7c73\u5149\u6e90\u4e0b\u7684\u56fa\u5316\u901f\u5ea6\u662f\u76f8\u540c\u6d53\u5ea6 I2959 \u5728 365 \u7eb3\u7c73\u5149\u6e90\u4e0b\u56fa\u5316\u901f\u5ea6\u7684\u8fd1\u4e24\u500d\uff0c\u800c\u4e14\u56fa\u5316\u6df1\u5ea6\u548c\u5747\u5300\u6027\u90fd\u6709\u660e\u663e\u6539\u5584\u3002\u8fd9\u76f4\u63a5\u610f\u5473\u7740\u6211\u4eec\u5728\u6784\u5efa\u7ec4\u7ec7\u5de5\u7a0b\u652f\u67b6\u65f6\u53ef\u4ee5\u66f4\u597d\u5730\u4fdd\u6301\u7ed3\u6784\u7684\u771f\u5b9e\u6027\u3002\r\n<h3><strong><b>II.\u6df1\u5165\u5206\u5b50\u5c42\u9762\uff1a\u89e3\u6784 LAP \u7684 \"\u6548\u7387 \"\u548c \"\u5b89\u5168\u6027<\/b><\/strong><\/h3>\r\n\u8bb8\u591a\u4ea7\u54c1\u624b\u518c\u53ea\u544a\u8bc9\u4f60\u7ed3\u679c\uff0c\u4f46\u4f5c\u4e3a\u4e00\u7ebf\u7814\u7a76\u4eba\u5458\uff0c\u6211\u4eec\u5fc5\u987b\u4e86\u89e3\u5176\u80cc\u540e\u7684 \"\u539f\u56e0\"\u3002\u8fd9\u53ef\u4ee5\u5e2e\u52a9\u60a8\u907f\u514d\u8bb8\u591a\u5e94\u7528\u9677\u9631\u3002\r\n<h4><strong>1.\u78f7\u9178\u9502\u76d0\u7ed3\u6784\uff1a\u6c34\u6eb6\u6027\u548c\u7ec6\u80de\u517c\u5bb9\u6027\u7684\u53cc\u91cd\u5bc6\u7801<\/strong><\/h4>\r\nLAP \u7684\u5316\u5b66\u5168\u79f0\u662f \"\u82ef\u57fa\uff082,4,6-\u4e09\u7532\u57fa\u82ef\u7532\u9170\u57fa\uff09\u78f7\u9178\u9502\"\u3002\u8fd9\u79cd \"\u9502\u76d0 \"\u7ed3\u6784\u662f\u5173\u952e\u6240\u5728\u3002\u5b83\u4f7f LAP \u5177\u6709\u60ca\u4eba\u7684\u6c34\u6eb6\u6027\uff0c\u5728\u7eaf\u6c34\u4e2d\u53ef\u8fbe\u5230\u7ea6 47 \u6beb\u514b\/\u6beb\u5347\uff0c\u51e0\u4e4e\u662f I2959 \u7684\u51e0\u5341\u500d\u3002\u9ad8\u6eb6\u89e3\u5ea6\u5bfc\u81f4\u4e86\u5747\u5300\u7684\u6eb6\u6db2\u72b6\u6001\uff0c\u8fd9\u662f\u5747\u5300\u4ea4\u8054\u7684\u7269\u7406\u57fa\u7840\u3002\r\n\r\n<div id=\"attachment_9544\" style=\"width: 3472px\" class=\"wp-caption alignnone\"><img decoding=\"async\" aria-describedby=\"caption-attachment-9544\" class=\"size-full wp-image-9544\" src=\"https:\/\/changhongchemical.com\/wp-content\/uploads\/2026\/02\/LAP-photoinitiator-.webp\" alt=\"LAP \u5149\u5f15\u53d1\u5242\" width=\"3462\" height=\"2084\" srcset=\"https:\/\/changhongchemical.com\/wp-content\/uploads\/2026\/02\/LAP-photoinitiator-.webp 3462w, https:\/\/changhongchemical.com\/wp-content\/uploads\/2026\/02\/LAP-photoinitiator--768x462.webp 768w, https:\/\/changhongchemical.com\/wp-content\/uploads\/2026\/02\/LAP-photoinitiator--1536x925.webp 1536w, https:\/\/changhongchemical.com\/wp-content\/uploads\/2026\/02\/LAP-photoinitiator--2048x1233.webp 2048w, https:\/\/changhongchemical.com\/wp-content\/uploads\/2026\/02\/LAP-photoinitiator--18x12.webp 18w, https:\/\/changhongchemical.com\/wp-content\/uploads\/2026\/02\/LAP-photoinitiator--1196x720.webp 1196w, https:\/\/changhongchemical.com\/wp-content\/uploads\/2026\/02\/LAP-photoinitiator--600x361.webp 600w\" sizes=\"(max-width: 3462px) 100vw, 3462px\" \/><p id=\"caption-attachment-9544\" class=\"wp-caption-text\">LAP \u5149\u5f15\u53d1\u5242<\/p><\/div>\r\n\r\n\u66f4\u91cd\u8981\u7684\u662f\uff0c\u5b83\u7684\u5149\u89e3\u4ea7\u7269\u76f8\u5bf9\u66f4\u7b80\u5355\uff0c\u9178\u6027\u66f4\u4f4e\u3002\u6211\u5728\u957f\u671f\u7ec6\u80de\u57f9\u517b\u5b9e\u9a8c\u4e2d\u76d1\u6d4b\u4e86\u57f9\u517b\u57fa\u7684 pH \u503c\u53d8\u5316\u3002\u4e0e\u4f7f\u7528 I2959 \u7684\u7cfb\u7edf\u76f8\u6bd4\uff0c\u4f7f\u7528 LAP \u56fa\u5316\u7684\u51dd\u80f6\u80fd\u4fdd\u6301\u66f4\u7a33\u5b9a\u7684\u73af\u5883 pH \u503c\uff0c\u8fd9\u5bf9\u4e8e\u9700\u8981\u7ef4\u6301\u6570\u5468\u7684\u7ec4\u7ec7\u57f9\u517b\u81f3\u5173\u91cd\u8981\u3002\r\n<h4><strong>2.405 \u7eb3\u7c73\u84dd\u5149\u6fc0\u53d1\uff1a\u4ece \"\u53ef\u5fcd\u53d7 \"\u5230 \"\u53cb\u597d \"\u7684\u98de\u8dc3<\/strong><\/h4>\r\nLAP \u7684\u6700\u5927\u5438\u6536\u6ce2\u957f\u7ea6\u4e3a 384 \u7eb3\u7c73\uff0c\u4e0e 405 \u7eb3\u7c73\u7684\u84dd\u5149 LED \u5b8c\u5168\u5339\u914d\u3002\u8fd9\u662f\u4e00\u4e2a\u6218\u7565\u4f18\u52bf\u3002\u7d2b\u5916\u7ebf\uff08\u5c24\u5176\u662f 365 \u7eb3\u7c73\u4ee5\u4e0b\u7684\u7d2b\u5916\u7ebf\uff09\u5177\u6709\u635f\u4f24 DNA \u7684\u98ce\u9669\uff0c\u8fd9\u5df2\u6210\u4e3a\u5171\u8bc6\u3002\u800c 405 \u7eb3\u7c73\u7684\u84dd\u5149\u5219\u8981\u5b89\u5168\u5f97\u591a\u3002\u5728\u6211\u4eec\u56e2\u961f\u5c01\u88c5\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7684\u5b9e\u9a8c\u4e2d\uff0c\u6211\u4eec\u53d1\u73b0\u4f7f\u7528 405 \u7eb3\u7c73\u56fa\u5316\u7ec4\u7684 24 \u5c0f\u65f6\u7ec6\u80de\u5b58\u6d3b\u7387\u6bd4\u4f7f\u7528 365 \u7eb3\u7c73\u7d2b\u5916\u7ebf\u56fa\u5316\u7ec4\u5e73\u5747\u9ad8\u51fa 15%-20%\u3002\r\n<h4><strong>\u6211\u7684\u5b9e\u7528\u6e05\u5355\u5149\u6e90\u9009\u62e9\u548c\u53c2\u6570\u4f18\u5316<\/strong><\/h4>\r\n<ul>\r\n \t<li><strong><b> \u9996\u9009\u5149\u6e90\uff1a<\/b><\/strong><\/li>\r\n<\/ul>\r\n\u9ad8\u5f3a\u5ea6 405 nm LED \u70b9\u5149\u6e90\u6216\u63a9\u819c\u5149\u523b\u673a\u3002LED \u5149\u6e90\u53d1\u70ed\u5c11\uff0c\u5149\u5f3a\u7a33\u5b9a\u3002\r\n<ul>\r\n \t<li><strong><b> \u5149\u7167\u5f3a\u5ea6\u662f\u5173\u952e\uff1a<\/b><\/strong><\/li>\r\n<\/ul>\r\n<strong><b>\u00a0<\/b><\/strong>\u5149\u5f3a\u4e0d\u4e00\u5b9a\u8d8a\u5f3a\u8d8a\u597d\u3002\u901a\u5e38\u60c5\u51b5\u4e0b\uff0c5-20 mW\/cm\u00b2 \u7684\u5149\u5f3a\u8303\u56f4\u662f\u5e73\u8861\u56fa\u5316\u901f\u5ea6\u548c\u7ec6\u80de\u5b89\u5168\u7684 \"\u6700\u4f73\u70b9\"\u3002\u5efa\u8bae\u5148\u8fdb\u884c\u5149\u5f3a\u68af\u5ea6\u5b9e\u9a8c\u3002\r\n<ul>\r\n \t<li><strong><b> \u66dd\u5149\u65f6\u95f4\uff1a<\/b><\/strong><\/li>\r\n<\/ul>\r\n\u7ed3\u5408\u5149\u7167\u5f3a\u5ea6\u8fdb\u884c\u8c03\u6574\u3002\u5bf9\u4e8e\u6d53\u5ea6\u4e3a 0.1%-0.25% \u7684 LAP\uff0c\u66dd\u5149\u65f6\u95f4\u4ece 10 \u79d2\u5230 60 \u79d2\u4e0d\u7b49\u3002\r\n<h3><strong><b>III.\u5b9e\u9a8c\u5ba4\u5b9e\u7528\u6307\u5357\uff1a\u5982\u4f55\u6709\u6548\u4f7f\u7528 LAP\uff1f<\/b><\/strong><\/h3>\r\n\u518d\u597d\u7684\u7406\u8bba\u4e5f\u9700\u8981\u5b9e\u9645\u5e94\u7528\u3002\u4ee5\u4e0b\u662f\u6211\u603b\u7ed3\u7684\u6b65\u9aa4\u548c\u5efa\u8bae\uff0c\u5e2e\u52a9\u4f60\u907f\u514d\u5e38\u89c1\u7684\u9677\u9631\u3002\r\n<h4><strong>1.\u51c6\u5907\u548c\u50a8\u5b58\uff1a\u7ec6\u8282\u51b3\u5b9a\u6210\u8d25<\/strong><\/h4>\r\nLAP \u662f\u4e00\u79cd\u7c89\u672b\uff0c\u867d\u7136\u5f88\u7a33\u5b9a\uff0c\u4f46\u5bf9\u6c34\u5206\u548c\u5149\u7ebf\u5f88\u654f\u611f\u3002\u6211\u7684\u505a\u6cd5\u5982\u4e0b\uff1a\r\n<ul>\r\n \t<li><strong><b> \u50a8\u5907\u6eb6\u6db2\u7684\u5236\u5907\uff1a <\/b><\/strong><\/li>\r\n<\/ul>\r\n\u7528\u68d5\u8272\u906e\u5149\u74f6\u914d\u5236 10-20 mL 1%\uff08w\/v\uff09\u50a8\u5907\u6db2\uff08\u5982 100 mg LAP \u6eb6\u4e8e 10 mL PBS \u6216\u53bb\u79bb\u5b50\u6c34\u4e2d\uff09\u3002\u7528 0.22 \u03bcm \u8fc7\u6ee4\u5668\u8fc7\u6ee4\u706d\u83cc\uff0c\u5206\u88c5\u6210\u5c0f\u4efd\uff08\u5982 1 mL\/\u7ba1\uff09\uff0c\u5728-20\u00b0C \u9ed1\u6697\u5904\u4fdd\u5b58\u3002\u8fd9\u6837\u53ef\u4fdd\u5b58\u4e00\u4e2a\u6708\uff0c\u907f\u514d\u53cd\u590d\u51bb\u878d\u5faa\u73af\u3002\r\n<ul>\r\n \t<li><strong><b> \u5de5\u4f5c\u6d53\u5ea6\uff1a <\/b><\/strong><\/li>\r\n<\/ul>\r\n\u5bf9\u4e8e\u5927\u591a\u6570\u7ec6\u80de\u5c01\u88c5\u5e94\u7528\u6765\u8bf4\uff0c0.05%-0.25% \u662f\u4e00\u4e2a\u5b89\u5168\u6709\u6548\u7684\u8d77\u59cb\u6d53\u5ea6\u8303\u56f4\u3002\u5bf9\u4e8e\u65e0\u7ec6\u80de\u6c34\u51dd\u80f6\u56fa\u5316\uff0c\u53ef\u4ee5\u5c1d\u8bd5\u4f7f\u7528\u66f4\u4f4e\u7684\u6d53\u5ea6\u3002\r\n<h4><strong>2.\u9488\u5bf9\u5177\u4f53\u5e94\u7528\u8fdb\u884c\u5fae\u8c03<\/strong><\/h4>\r\n<ul>\r\n \t<li><strong><b> \u9ad8\u7cbe\u5ea6\u751f\u7269\u4e09\u7ef4\u6253\u5370\uff1a<\/b><\/strong><\/li>\r\n<\/ul>\r\n<strong><b>\u00a0<\/b><\/strong>\u5982\u679c\u60a8\u7684\u751f\u7269\u58a8\u6c34\u7c98\u5ea6\u8f83\u9ad8\uff0c\u6253\u5370\u901f\u5ea6\u8f83\u6162\uff0c\u5efa\u8bae\u4f7f\u7528\u6d53\u5ea6\u8303\u56f4\u7684\u4e0a\u9650\uff08\u5982 0.2%-0.25%\uff09\uff0c\u4ee5\u786e\u4fdd\u6324\u51fa\u7ea4\u7ef4\u5728\u6324\u51fa\u540e\u8fc5\u901f\u51dd\u56fa\uff0c\u4fdd\u8bc1\u7ed3\u6784\u7cbe\u5ea6\u3002\r\n<ul>\r\n \t<li><strong><b> \u76f4\u63a5\u7535\u6c60\u5c01\u88c5 <\/b><\/strong><\/li>\r\n<\/ul>\r\n\u4e3a\u4e86\u6700\u5927\u9650\u5ea6\u5730\u63d0\u9ad8\u7ec6\u80de\u517c\u5bb9\u6027\uff0c\u5e94\u4f7f\u7528\u6d53\u5ea6\u8303\u56f4\u7684\u4f4e\u7aef\uff08\u5982 0.05%-0.1%\uff09\uff0c\u5e76\u9002\u5f53\u5ef6\u957f\u66dd\u5149\u65f6\u95f4\uff0c\u4f46\u5149\u7167\u5f3a\u5ea6\u8981\u9002\u4e2d\u3002\"\u4f4e\u6d53\u5ea6\u3001\u957f\u66dd\u5149 \"\u901a\u5e38\u6bd4 \"\u9ad8\u6d53\u5ea6\u3001\u77ed\u66dd\u5149 \"\u5bf9\u7ec6\u80de\u66f4\u6e29\u548c\u3002\r\n<ul>\r\n \t<li><strong><b> \u8fd9\u662f\u6211\u7ecf\u5e38\u88ab\u95ee\u5230\u7684\u4e00\u4e2a\u95ee\u9898\uff1a<\/b><\/strong><\/li>\r\n<\/ul>\r\n<strong><b>\"\u7d2b\u5916\u7ebf\uff08365 \u7eb3\u7c73\uff09\u80fd\u6fc0\u53d1 LAP \u5417\uff1f<\/b><\/strong>\r\n\r\n\u7b54\u6848\u662f\uff1a\u53ef\u4ee5\uff0c\u4f46\u6548\u7387\u5e76\u4e0d\u7406\u60f3\u3002LAP \u5728 365 \u7eb3\u7c73\u6ce2\u957f\u5904\u4e5f\u6709\u5438\u6536\uff0c\u4f46\u5176\u6469\u5c14\u6d88\u5149\u7cfb\u6570\u4f4e\u4e8e\u5176\u5728 384 \u7eb3\u7c73\u6ce2\u957f\u5904\u7684\u7279\u5f81\u5cf0\u503c\u3002\u8fd9\u610f\u5473\u7740\u60a8\u53ef\u80fd\u9700\u8981\u7a0d\u5fae\u589e\u52a0\u6d53\u5ea6\u6216\u66dd\u5149\u65f6\u95f4\u3002\u56e0\u6b64\uff0c\u9664\u975e\u53d7\u8bbe\u5907\u9650\u5236\uff0c\u5426\u5219\u8bf7\u575a\u6301\u4f7f\u7528 405 \u7eb3\u7c73\u5149\u6e90\u3002\r\n<h3><strong><b>III.\u5b9e\u9a8c\u5ba4\u5b9e\u7528\u6307\u5357\uff1a\u5982\u4f55\u6709\u6548\u4f7f\u7528 LAP\uff1f<\/b><\/strong><\/h3>\r\n\u518d\u597d\u7684\u7406\u8bba\u4e5f\u9700\u8981\u5b9e\u9645\u5e94\u7528\u3002\u4ee5\u4e0b\u662f\u6211\u603b\u7ed3\u7684\u6b65\u9aa4\u548c\u5efa\u8bae\uff0c\u5e2e\u52a9\u4f60\u907f\u514d\u5e38\u89c1\u7684\u9677\u9631\u3002\r\n<h4><strong>1.\u51c6\u5907\u548c\u50a8\u5b58\uff1a\u7ec6\u8282\u51b3\u5b9a\u6210\u8d25<\/strong><\/h4>\r\nLAP \u662f\u4e00\u79cd\u7c89\u672b\uff0c\u867d\u7136\u5f88\u7a33\u5b9a\uff0c\u4f46\u5bf9\u6c34\u5206\u548c\u5149\u7ebf\u5f88\u654f\u611f\u3002\u6211\u7684\u505a\u6cd5\u5982\u4e0b\uff1a\r\n<ul>\r\n \t<li><strong><b> \u50a8\u5907\u6eb6\u6db2\u7684\u5236\u5907\uff1a<\/b><\/strong><\/li>\r\n<\/ul>\r\n\u7528\u68d5\u8272\u906e\u5149\u74f6\u914d\u5236 10-20 mL 1%\uff08w\/v\uff09\u50a8\u5907\u6db2\uff08\u5982 100 mg LAP \u6eb6\u4e8e 10 mL PBS \u6216\u53bb\u79bb\u5b50\u6c34\u4e2d\uff09\u3002\u7528 0.22 \u03bcm \u8fc7\u6ee4\u5668\u8fc7\u6ee4\u706d\u83cc\uff0c\u5206\u88c5\u6210\u5c0f\u4efd\uff08\u5982 1 mL\/\u7ba1\uff09\uff0c\u5728-20\u00b0C \u9ed1\u6697\u5904\u4fdd\u5b58\u3002\u8fd9\u6837\u53ef\u4fdd\u5b58\u4e00\u4e2a\u6708\uff0c\u907f\u514d\u53cd\u590d\u51bb\u878d\u5faa\u73af\u3002\r\n<ul>\r\n \t<li><strong><b> \u5de5\u4f5c\u6d53\u5ea6\uff1a<\/b><\/strong><\/li>\r\n<\/ul>\r\n\u5bf9\u4e8e\u5927\u591a\u6570\u7ec6\u80de\u5c01\u88c5\u5e94\u7528\u6765\u8bf4\uff0c0.05%-0.25% \u662f\u4e00\u4e2a\u5b89\u5168\u6709\u6548\u7684\u8d77\u59cb\u6d53\u5ea6\u8303\u56f4\u3002\u5bf9\u4e8e\u65e0\u7ec6\u80de\u6c34\u51dd\u80f6\u56fa\u5316\uff0c\u53ef\u4ee5\u5c1d\u8bd5\u4f7f\u7528\u66f4\u4f4e\u7684\u6d53\u5ea6\u3002\r\n<h4><strong>2.\u9488\u5bf9\u5177\u4f53\u5e94\u7528\u8fdb\u884c\u5fae\u8c03<\/strong><\/h4>\r\n<ul>\r\n \t<li><strong><b> \u9ad8\u7cbe\u5ea6\u751f\u7269\u4e09\u7ef4\u6253\u5370\uff1a<\/b><\/strong><\/li>\r\n<\/ul>\r\n\u5982\u679c\u60a8\u7684\u751f\u7269\u58a8\u6c34\u7c98\u5ea6\u8f83\u9ad8\uff0c\u6253\u5370\u901f\u5ea6\u8f83\u6162\uff0c\u5efa\u8bae\u4f7f\u7528\u6d53\u5ea6\u8303\u56f4\u7684\u4e0a\u9650\uff08\u5982 0.2%-0.25%\uff09\uff0c\u4ee5\u786e\u4fdd\u6324\u51fa\u7ea4\u7ef4\u5728\u6324\u51fa\u540e\u8fc5\u901f\u51dd\u56fa\uff0c\u4fdd\u8bc1\u7ed3\u6784\u7cbe\u5ea6\u3002\r\n<ul>\r\n \t<li><strong><b> \u76f4\u63a5\u7535\u6c60\u5c01\u88c5<\/b><\/strong><\/li>\r\n<\/ul>\r\n\u4e3a\u4e86\u6700\u5927\u9650\u5ea6\u5730\u63d0\u9ad8\u7ec6\u80de\u517c\u5bb9\u6027\uff0c\u5e94\u4f7f\u7528\u6d53\u5ea6\u8303\u56f4\u7684\u4f4e\u7aef\uff08\u5982 0.05%-0.1%\uff09\uff0c\u5e76\u9002\u5f53\u5ef6\u957f\u66dd\u5149\u65f6\u95f4\uff0c\u4f46\u5149\u7167\u5f3a\u5ea6\u8981\u9002\u4e2d\u3002\"\u4f4e\u6d53\u5ea6\u3001\u957f\u66dd\u5149 \"\u901a\u5e38\u6bd4 \"\u9ad8\u6d53\u5ea6\u3001\u77ed\u66dd\u5149 \"\u5bf9\u7ec6\u80de\u66f4\u6e29\u548c\u3002\r\n<ul>\r\n \t<li><strong><b> \u8fd9\u662f\u6211\u7ecf\u5e38\u88ab\u95ee\u5230\u7684\u4e00\u4e2a\u95ee\u9898\uff1a<\/b><\/strong><\/li>\r\n<\/ul>\r\n&#8220;Can LAP be excited with UV light (365 nm)?&#8221;\r\n\r\nThe answer is: Yes, but the efficiency is not optimal. LAP also absorbs at 365 nm, but the molar extinction coefficient is lower than its characteristic peak at 384 nm. This means you may need to slightly increase the concentration or exposure time. Therefore, unless limited by equipment, please stick to a 405 nm light source.\r\n<h3><strong><b>IV.\u5c55\u671b\u672a\u6765\uff1aLAP \u4e4b\u540e\uff0c\u4e0b\u4e00\u4e2a\u7a81\u7834\u70b9\u5728\u54ea\u91cc\uff1f<\/b><\/strong><\/h3>\r\nLAP has significantly advanced the field of biomanufacturing. However, based on discussions with my colleagues, the next frontier may be &#8220;dynamic photocuring.&#8221;\r\n\r\nCurrently, we use one-time, irreversible curing. But in the future, will it be possible to develop photoinitiator systems that respond to specific wavelengths (such as far-red light or two-photon excitation), and whose curing degree or mechanical properties can be &#8220;adjusted on demand&#8221; or &#8220;locally erased&#8221;? Imagine printing a cardiac patch and then being able to remotely and gradually adjust its hardening process using non-invasive deep-tissue light to better match the growth rhythm of the native tissue. This might require entirely new molecular designs, such as coupling LAP&#8217;s photosensitive groups with reversible reaction\r\n\r\n<strong><b>\u6700\u540e\uff0c\u6211\u60f3\u5411\u4f60\u4eec\u63d0\u51fa\u4e00\u4e2a\u95ee\u9898\uff1a<\/b><\/strong>\u00a0\u5728\u5177\u4f53\u7814\u7a76\u6216\u5e94\u7528\u4e2d\u4f7f\u7528 LAP \u65f6\uff0c\u60a8\u9047\u5230\u7684\u6700\u5927\u6311\u6218\u662f\u4ec0\u4e48\uff1f\u662f\u63a7\u5236\u51dd\u56fa\u51dd\u80f6\u7684\u673a\u68b0\u6027\u80fd\uff0c\u8fd8\u662f\u5b9e\u73b0\u4e0e\u7279\u5b9a\u7c7b\u578b\u7ec6\u80de\u5171\u57f9\u517b\u7684\u957f\u671f\u7a33\u5b9a\u6027\uff1f\u8bf7\u5206\u4eab\u60a8\u7684\u7ecf\u9a8c\uff0c\u6211\u4eec\u4e00\u8d77\u6765\u8ba8\u8bba\u3002\r\n\r\n&nbsp;\n\n\n<p><strong>Related product references:<\/strong> For formulation review or sourcing comparison, see <a href=\"https:\/\/changhongchemical.com\/product\/chluminit-tmo-photoinitiator-cas-270586-78-2\/\">CHLUMINIT TMO<\/a> \u548c <a href=\"https:\/\/changhongchemical.com\/product\/photoinitiator-819-irgacure-819-cas-162881-26-7\/\">CHLUMINIT 819<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"<p>Hi, I&#8217;m Starry. I&#8217;ve been working with photocurable materials in the lab for over a decade. If you&#8217;re struggling with uneven hydrogel curing or unsatisfactory cell viability in bioprinting, or if you&#8217;re frustrated with&#8230;<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[185],"tags":[],"class_list":["post-9542","post","type-post","status-publish","format-standard","hentry","category-photoinitiator"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>From I2959 to LAP:Photoinitiator- Changhong Chemical<\/title>\n<meta name=\"description\" content=\"Comprehensive guide to LAP photoinitiator for hydrogel research &amp; bioprinting. Learn why LAP outperforms I2959 in biocompatibility, 405nm curing efficiency, and cell viability. Get expert protocols for stock preparation, light optimization (5-20 mW\/cm\u00b2), and applications in 3D bioprinting &amp; cell encapsulation.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/changhongchemical.com\/zh\/from-i2959-to-lap-my-journey-of-upgrading-hydrogel-photocuring-technology\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"From I2959 to LAP:Photoinitiator- Changhong Chemical\" \/>\n<meta property=\"og:description\" content=\"Comprehensive guide to LAP photoinitiator for hydrogel research &amp; bioprinting. Learn why LAP outperforms I2959 in biocompatibility, 405nm curing efficiency, and cell viability. 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